In the frame of the Projet Call “Biomedicine: improving yields and control production costs” of the Grand Défi Bioproduction, the ACCESS (Advanced Cell Control by Spectroscopic Sensors) R&D project, received a favorable funding from BPI France to meet the societal challenge of producing Innovative Therapy Medicines at lower costs.
The ACCESS project aims to optimize Mesenchymal Stem Cell (MSC) cultures in a bioreactor through on-line production control, based on innovative in-line optical sensors, Machine Learning algorithms and automated real-time feedback coupled with a digital twin and a Quality-by-Design (QbD) approach for process modeling.
The consortium of this collaborative project is composed of the integrator MTInov and 5 complementary partners: INDATECH – Chauvin Arnoux group, Ondalys, Cybernano, Ypso Facto and StemInov.
This project will make it possible to structure an integrated French QbD / PAT offer with European influence for the control of all types of adherent cell cultures in biotechnology, thanks to suppliers of complementary products and services, ranging from process modeling (Ypso Facto, Cybernano ) up to the industrial implementation of online control (INDATECH, Ondalys, Cybernano).
To know more about Ondalys expertise in Process Supervision in the frame of Industry 4.0.